Profils actuels chez COREPA

Offres d'emploi chez COREPA

Documents COREPA

• Chapter 10 Mechanism-Based Modeling of Estrogen Receptor Binding. Affinity: A Common Reactivity Pattern (COREPA) Implementation.229. Ovanes Mekenyan and Rossitsa Serafimova. Chapter 11 Molecular Field Analysis Methods for Modeling Endocrine. D
  http://www.fda.gov/downloads/ScienceResearch/BioinformaticsTools/EndocrineDisruptorKnowledgebase/UCM158628.pdf
• (e.g. AR binding). COREPA is a unique SAR approach designed to. analyze reactivity patterns' of structurally diverse but ... COREPA consisted of the following steps: (1) multiple conformers within 20 kcal/mol of the lowest. energ
  http://www.fda.gov/downloads/ScienceResearch/BioinformaticsTools/EndocrineDisruptorKnowledgebase/UCM144380.pdf
• Recently, the COmmon REactivity PAttern (COREPA) approach was developed as a probabilistic classification ... In the initial version of COREPA, the proba- bility distributions for only one stereoelectronic parameter. at a time we
  http://ambit.acad.bg/nina/publications/2004/Corepa-M%20reprint.pdf
• Environmental and Human Toxicity in EnV-S. Ecological and Human Health Impacts in EnV-S. Currently based on LD50, LC50, RfD, RfC. These endpoints form the basis of chemical management and regulation in the U.S., but they are often unavailable ...
  http://blowers.chee.arizona.edu/LCAworkingroup/boyd_041304_telesem.ppt
• energetically reasonable conformers are taken into account to derive the common reactivity pattern (COREPA) of structurally ... interest, should possess a commonality in the values of their steric and/or electronic parameters, thus yiel
  http://ambit.acad.bg/nina/publications/2003/3DQSAR.pdf